Description
FOXO4-DRI is a D-retro-inverso peptide — built from D-amino acids in reversed sequence — designed to disrupt the interaction between FOXO4 and p53 inside senescent cells.
In the landmark published work, this interference selectively pushed senescent cells into apoptosis, restoring fitness markers in naturally aged mice — a foundational result in senolytics, one of the most active areas of ageing research.
Format & handling
Supplied as a lyophilized powder in a sealed, batch-stamped vial. Store sealed at −20 °C protected from light. For laboratory work, reconstitute with bacteriostatic water shortly before use and refrigerate any working solution at 2–8 °C.
For laboratory research use only — not for human or veterinary use. The summary above describes published research for scientific context and makes no claims about this product.
